Biological Effects Ectopic Production Of Bioactive Substances	

Although bioactive substances produced and functioning in a paracrine or autocrine fashion are not associated with ectopic humoral syndromes, the biological implications of these substances are now recognised to be important in understanding the biological characteristics of neoplastic cells and in developing new modalities of cancer therapies.

The mechanism by which ectopic production of a bioactive substance causes biological effects can be classed as one of the following:

• Endocrine Effects
• Paracrine Effects
• Autocrine Effects